Multiplex Image Analysis Workshop : Preliminary Program

24 Sep - 25 Sep

Tuesday, September 24, 2024 Start End Location

Registration

12:00 13:00 Entrance and lobby

Multiplexing methods and techniques

Session Chair: Sripad Ram

13:00 17:45 Main seminar room

Introduction to multiplex image analysis - Sripad Ram

This will be an introductory talk that provides an overview of tissue multiplexing technologies and the current challenges in the analysis of multiplexing data.

13:00 13:30

Comprehensive Profiling & Interactive Exploration of Multiplexed Immunofluorescence Images of Murine Whole Brain Slices # 109

Badrinath Roysam , Hien Van Nguyen , Saurabh Prasad , Rachel W. Mills , Jahandar Jahanipour , Xiaoyang Li , Aditi Singh , John B. Redell , Pramod Dash , Dragan Maric

University of Houston, Houston, United States,

13:30 14:00

Evaluating the TME using Chromogenic Multiplexed IHC and Deep Learning # 90

Kouther Noureddine , Calum MacAulay , Anna McGuire , Martial Guillaud , Paul Gallagher

BC Cancer Research Centre, Vancouver, Canada,

14:00 14:30

Molecular Pathology in Preclinical Safety Assessments # 105

Nathan Roscoe , Mathieu Marella

Johnson & Johnson Innovative Medicine, San diego, United States,

14:30 15:00

Coffee break

Time for coffee, tea, cookies, networking and to visit the exhibits

15:00 15:45

Quantitative 3D Imaging of bleomycin-induced pulmonary fibrosis in mouse lung # 106

Francios Olivier , Pradeep Rajasekhar , Mhairi Maxwell , Hojin Chang , Lachlan Whitehead , Greg Bass , Verena Wimmer , Kelly Rogers

CSL Innovation, Melbourne, Australia,

15:45 16:15

Segmentation error aware clustering, dimensionality reduction, and integration for highly multiplexed imaging data # 86

Yuju Lee , Kieran R. Campbell

University of Toronto, Toronto, Canada,

16:15 16:45

Exploring interplay between tumor intrinsic features & immune cell phenotypes in multi-tumor tissue microarrays by a single step 15-plex fluorescence IHC & imaging on the Orion Platform # 85

Richard VanKrieken , Jo Bender , Sophia Kekchidou , Michelle Burgin , Kristen Ruma , Naveen Dakappagari , Jennifer Bordeaux

Navigate BioPharma Services, Carlsbad, United States,

16:45 17:00

Sponsored presentation - Canopy Biosciences

17:00 17:30 Main seminar room

Short break

17:30 17:45

Panel discussion - IT challenges for mxIF datasets

Session Chair: Peter Sobolewski

17:45 18:30 Main seminar room

Chunky Yet Funky: The Future of Data Management in Multiplex 'Omics Imaging # 102

Peter Sobolewski

The Jackson Laboratory, Farmington, United States,

17:45 18:00

Panel discussion - Q&A

18:00 18:30

Dinner

18:30 20:30 Main lobby area
Wednesday, September 25, 2024 Start End Location

Nuclear/cell segmentation and phenotyping

09:00 10:45 Main seminar room

Quantitative and standardized pipeline for comparing nuclear segmentation platforms # 107

Shachi Mittal

University of Washington, Seattle, United States,

09:00 09:30

Deep-learning strategies for single-cell phenotyping in multiplex image analysis # 87

Harry Nunns

NeoGenomics Laboratory, Aliso Viejo, United States,

09:30 10:00

One Pixel to Many Objects Mapping for Nuclear Segmentation and Marker Evaluation in Spatial Biology # 91

Calum MacAulay , Shunsuke Ishige , Puneet Arora , Paul Gallagher , Martial Guillaud

BC Cancer Research Institute, Vancouver, Canada,

10:00 10:30

Benchmarking Cell Segmentation of MIBI and Lunaphore Images with Open-Source Software # 98

Mary Edith Brown

University of Minnesota - Twin Cities, Minneapolis, United States,

10:30 10:45

Coffee break

Time for coffee, tea, cookies, networking and to visit the exhibits

10:45 11:30

Multiplex image analysis - software features

11:30 12:15 Main seminar room

ariadne.ai SPATIAL: An intuitive workflow for multiplex image data analysis # 110

Fabian Nicolas Svara

ariadne.ai, Buchrain, Switzerland,

11:30 11:45

Q&A and discussion

11:45 12:15

Sponsored presentation-Rarecyte

Session Chair: Sripad Ram

12:15 12:45 Main seminar room

Lunch

12:45 14:00 Main lobby area

Multiplex image analysis applications

14:00 15:30 Main seminar room

Connections Across Scale: From Molecules to Multicell Modules # 101

John W. Hickey

Duke University, Durham, United States,

14:00 14:30

Unraveling functionally distinct metabolic programs to predict immunotherapy response in non-small cell lung cancer (NSCLC) # 93

Filippo Pullara

PredxBio, Inc., Pittsburgh, United States,

14:30 15:00

Single Cell Spatial Biomarkers in Lymphoma - Akil Merchant

15:00 15:30

Coffee break

Time for coffee, tea, cookies, networking and to visit the exhibits

15:30 16:15

Multimodal approaches

16:15 17:15 Main seminar room

Spatial Instruction of T Cell Barrier Defense # 104

Miguel Reina-Campos

La Jolla Institute for Immunology, La Jolla, United States,

16:15 16:45

SpaceIQ™ – Cloud-Based Spatial Multi-Omics Software Platform with an Intelligent Suite of Unbiased Spatial Analytics and Explainable AI Tools # 96

Brian Falkenstein , Raymond Yan , Shannon Quinn , Akif Burak Tosun , Chakra Chennubhotla , Filippo Pullara

PredxBio, Inc., Pittsburgh, United States,

16:45 17:15

Short talks

17:15 18:15 Main seminar room

Unexpected Benefits of Web Tools for Scientific Image Processing in the Age of AI # 100

Andrey Aristov

Institut Pasteur, Paris, France,

17:15 17:30

Large-scale DNA Organization Identifies Aggressive Prostate Cancer in Low and Intermediate-Risk Patients Treated with Radical Prostatectomy # 97

Fumiya Inaba , Zhaoyang Chen , Anita Carraro , Paul Gallagher , Miha Pukl , Mira Keyes , Calum MacAulay , Martial Guillaud

BC Cancer Research Institute, Vancouver, Canada,

17:30 17:45

Short break

17:45 18:00

Sponsored presentation - Navigating the multiplex image analysis workflow: ​from images to​ data-driven insights - Lunaphore

18:00 18:30 Main seminar room

GALA DINNER & poster session

18:45 20:45 Main lobby area
September 25 (Wednesday): GALA DINNER & poster session
18:09 - 20:09

Quantitative analysis of chronic lymphocytic leukemia samples obtained by single-shot 17-plex staining followed by imaging with the Orion™ spatial biology platform # 89

Katrina Sanders , Edward Lo , Tad George , Antonio Cosma , Jérôme Paggetti , Martina Seiffert , Etienne Moussay , Selena Larkin

RareCyte, Inc, Seattle, United States,

Challenges of multiplexed imaging on a core facility # 95

Aurélie Doméné , Perrine Paul-Gilloteaux

Nantes Université, Nantes, France,

Large-scale DNA Organization Identifies Aggressive Prostate Cancer in Low and Intermediate-Risk Patients Treated with Radical Prostatectomy # 97

Fumiya Inaba , Zhaoyang Chen , Anita Carraro , Paul Gallagher , Miha Pukl , Mira Keyes , Calum MacAulay , Martial Guillaud

BC Cancer Research Institute, Vancouver, Canada,