QBI 2020 Conference Sessions

6 Jan - 9 Jan

Thursday January 9

Registration Desk Opens

08:00 14:00 Registration Desk/Area

Keynote Lecture: Wolfgang Baumeister

Session Chair: Alessandra Cambi

08:30 09:10 Room 1

Structural biology in situ: The promise and challenges of cryo-electron tomography (# 617)

Wolfgang Baumeister
Max Planck Institute of Biochemistry, , DE

08:30 09:10

Tutorial: Quantitative Phase Imaging

Session Chair: Jörg Enderlein

09:10 09:40 Room 1

Quantitative Phase Imaging (# 396)

Alexander Jesacher
Medical University of Innsbruck,

09:10 09:40

Coffee Break

09:40 10:10 Foyer

Minisymposium: Correlative Microscopy

Session Chair: Diane Lidke

10:10 11:10 Room 1

Imaging the nanoscale structure of endocytosis with correlative super-resolution light and electron microscopy. (# 577)

Justin W Taraska, Kem Sochacki
National Institutes of Health,

10:10 10:30

Towards quantitative correlative microscopy (# 528)

Lucy M Collinson
Francis Crick Institute,

10:30 10:50

Live-cell correlative microscopy of single organelles (# 590)

Nalan Liv
University Medical Center Utrecht,,

10:30 10:50

Session: Correlative/multimodal microscopy

Session Chair: Alessandra Cambi

11:10 12:10 Room 1

Multimodal and multicolour microscopy to identify biomolecules in large-scale EM (# 310)

Pascal de Boer, Aditi Srinivasa Raja, Jacob Hoogenboom, Ben Giepmans
University Medical Center Groningen,

11:10 11:25

Quantitative 3D super-resolution imaging of chromatin ‘blobs’ (# 420)

Lothar Schermelleh
University of Oxford,

11:25 11:40

Cryo-CARE Facilitates Sub-Tomogram Averaging in Cryo Transmission Electron Microscopy (# 453)

Tim-Oliver Buchholz, Mareike Jordan, Gaia Pigino, Florian Jug
MPI-CBG/CSBD,

11:40 11:55

Towards correlative multimodal nanospectroscopy (# 329)

Iztok Urbancic, Falk Schneider, Erdinc Sezgin, Silvia Galiani, Christian Eggeling
Jozef Stefan Institute,

11:55 12:10

Session: Tracking

Session Chair: Sean Andersson

10:10 12:10 Room 2

Novel particle tracking approach with CNN-based candidate selection and two-step linking by Bayesian network (# 503)

Mariia Dmitrieva, Jens Rittscher
University of Oxford,

10:10 10:25

Precise mapping of intracellular diffusion and drift from SPT data analysis (# 409)

Antoine Salomon, Charles Kervrann
Inria Rennes, Rennes, FR

10:25 10:40

Probabilistic overall reconstruction of membrane-associated molecular dynamics from partial observations in rod-shaped bacteria (# 390)

Yunjiao LU, Charles Kervrann, Alain Trubuil, Pierre Hodara
INRA, Jouy-en-Josas, FR

10:40 10:55

A 2-step algorithm for the estimation of time-varying Single Particle Tracking models (# 381)

Boris I Godoy, Ye Lin, Sean Andersson
Boston University, Boston, US

10:55 11:10

Single-Particle Diffusion Characterization by Deep Learning (# 359)

Yoav Shechtman, Naor Granik, Yael Roichman, Lucien E Weiss, Elias E Nehme, Eran Perlson
Technion, Israel Institute of Technology, Haifa, IL

11:10 11:25

Faster FLImP – Towards High throughput image acquisition and track selection (# 341)

Ben Davis, Michail Vrettas, Michael Hirsch, Sarah Needham, Marisa Martin-Fernandez, Daniel James Rolfe
STFC,

11:25 11:40

Quantitative Comparison of Single Particle Tracking Algorithms Across Different Signal and Noise Levels (# 275)

Ye Lin, Sean B. Andersson
Boston University,

11:40 11:55

Effect of pixelation on the parameter estimation of single molecule trajectories (# 569)

Milad Rafiee Vahid, Bernard Hanzon, Raimund J. Ober
University of Southampton, College Station, US

11:55 12:10

Lunch (provided)

12:10 13:30 Food Area

Minisymposium: Tissue Multiplexing Techniques and Applications in Oncology I

Session Chair: Jens Rittscher

13:30 15:30 Room 1

Introduction to the minisymposium on tissue multiplexing – is more the merrier or messier? (# 591)

Sripad Ram
Pfizer, Inc., , United States

13:30 13:40

Multiplex immunohistochemistry and transcriptomic data (# 593)

Robert West
Stanford University Medical Center,

13:40 14:00

Implementation of multiplexing and image analysis to support drug discovery and development (# 571)

Shanon Seger
Roche,

14:00 14:20

Deep Learning approaches for reliable quantification of muti-omics cell imaging datasets to interrogate RNA and protein spatial and temporal subcellular interactions (# 291)

Emmanuel Bouilhol, Macha Nikolski, Benjamin Dartigues, Hayssam Soueidan, Robyn Brackin, Anca savulescu, Musa Mhlanga
INSERM, Merignac, FR

14:20 14:35

Understanding and Modeling Inflammation Induced Immuno-Suppression in Tumors Using Multi-plex Immunofluorescence and Live Cell Microscopy (# 336)

Stephen Lockett, Anne Gilmore, William Heinz, David Scheiblin, Sarah Flaherty, Noemi Kedei, Veena Somasundaram, Lisa Ridnour, Adelaide Wink, Caleb Kim, Valentin Magidson, Erina Kamiya, Jinqiu Chen, David Wink
National Cancer Institute,

14:35 14:55

Highly multiplexed imaging in health and disease by imaging mass cytometry (# 607)

Bernd Bodenmiller
University of Zurich,

14:55 15:15

Multimodal mass spectrometry imaging of tumours (# 550)

Josephine Bunch
National Physical Laboratory,

15:15 15:30

Session: Methods for Single Molecule Analysis

Session Chair: Keith A Lidke

13:30 15:30 Room 2

Single Molecule Localization Microscopy using time modulated illumination (# 481)

Pierre Jouchet, Clement Cabriel, Nicolas Bourg, Marion Bardou, Christian Poüs, Emmanuel Fort, Sandrine Leveque-Fort
CNRS, Orsay Cedex, FR

13:30 13:45

Identifying analysis algorithm induced image artefacts in localisation microscopy (# 469)

Richard John Marsh, Ishan Costello, Susan Cox
King's College London, London, GB

13:45 14:00

SIMPLE: Structured illumination based point localization estimator with enhanced precision (# 386)

Loïc Reymond, Stefan Wieser, Verena Ruprecht
ICFO - The Institute of Photonic Sciences,

14:15 14:30

Spatiotemporal Resolution as an Information Theoretical Property of Stochastic Optical Localization Nanoscopy (# 369)

Yi Sun
The City College of City University of New York, New York, US

14:30 14:45

Haste makes waste – Slow imaging increases resolution and labeling efficiencies in SMLM (# 322)

Robin Diekmann, Maurice Kahnwald, Jonas Ries
EMBL,

14:45 15:00

Towards Bayesian based smart microscopy (# 283)

Juliette Griffie, Paul Rolland, Daniel Sage, Robin Lang, Volkan Cevher, Suliana Manley
EPFL, Lausanne, CH

15:00 15:15

Single molecule localisation lightfield microscopy (# 290)

Leila A Muresan
University of Cambridge, Cambridge, GB

15:15 15:30

Coffee Break

15:30 16:00 Foyer

Minisymposium: Tissue Multiplexing Techniques and Applications in Oncology II

Session Chair: Sripad Ram

16:00 16:55 Room 1

Multiplex Immune Cell Profiling to Gain Insights into Progression in Early Cancer (# 484)

Jens Rittscher, Natalia Garcia Martin
University of Oxford,

16:00 16:15

Towards computational multiplex fluorescence microscopy: Machine learning-based integrated prediction of morphological and molecular tumor profiles (# 627)

Frederick Klauschen
Charité University Hospital Berlin,

16:15 16:35

Multiplex imaging of lung tumours with CODEX technology (# 584)

Marta Trüb, Petra Herzig, Nicole Kirchhammer, Franziska Werner, Kirsten Mertz, Viktor Kölzer, Abhishek Kashyap, Alfred Zippelius
University of Basel / University Hospital Basel,

16:35 16:55

Session: Probe Development

Session Chair: Daniel Wuestner

17:00 17:45 Room 1

Mechanical investigations of mEos4b blinking: longer single particle tracking with less track interruptions. (# 311)

Siewert Hugelier, Elke De Zitter, Daniel Thédié, Viola Monkemöller, Joel Beaudouin, Virgile Adam, Martin Byrdin, Luc Vanmeervelt, Dominique Bourgeois, Peter Dedecker
KU Leuven, Heverlee, BE

17:00 17:15

Separation of cell signalling responses based on a new model for photoswitching in FRET biosensors (# 380)

Thijs Roebroek
KULeuven,

17:15 17:30

Innovative buffer for long-lived fluorescence imaging for 2D and 3D dSTORM (# 357)

Angelina Provost, corentin Rousset, Camille Fourneaux, Philippe Bouvet, Jean-Jacques Diaz, Catherine Ladavière, marie-therese charreyre, Arnaud Favier, Christophe Place, Karine MONIER
CRCL,

17:30 17:45

Session: Point spread function analysis

Session Chair: Yoav Shechtman

16:00 17:15 Room 2

PSF-broadening due to fluorescence emission: principle and implications on imaging (# 288)

Jan Becker, Rainer Heintzmann
Leibniz Institute for Photonic Technology,

16:00 16:15

Simultaneous multicolor single-molecule imaging using discrete PSF engineering (# 379)

Wim Vandenberg, Marcel Leutenegger, Fabian Hertel, Bartosz Krajnik, Arno Bouwens, Robin Van den Eynde, Ezra Bruggeman, Thomas Schlichthärle, Alexander Auer, Ralf Jungmann, Peter Dedecker
KU Leuven, Leuven, BE

16:15 16:30

Measurement of the depth-dependence of point spread functions near the glass-water interface in high-numerical aperture microscopy (# 373)

Petar N Petrov, William E. Moerner
University of California, Berkeley, Stanford, US

16:30 16:45

A General Framework for Fitting an Arbitrary Model to SMLM Data (# 312)

Yu-Le Wu, Markus Mund, Philipp Hoess, Aline Tschanz, Jonas Ries
EMBL, Heidelberg, DE

16:45 17:00

ZOLA-3D: a software for optimal 3D SMLM with arbitrary PSF (# 524)

Benoit Lelandais, MICKAEL LELEK, Jonas Ries, Christophe Zimmer
Institut Pasteur, paris, FR

17:00 17:15

Session: Machine Learning

Session Chair: Christopher P Calderon

17:15 18:00 Room 2

DeepFocus: a Near One-Shot Micro-Manager Auto-focus Plugin using Convolutional Neural Networks (# 388)

Adrian Shajkofci, Michael Liebling
Idiap Research Institute, Martigny, CH

17:15 17:30

Probabilistic Noise2Void: Unsupervised Content-Aware Denoising (# 473)

Alexander Krull, Tomas Vicar, Mangal Prakash, Manan Lalit, Florian Jug, Pavel Tomancak
MPI-CBG/CSBD,

17:30 17:45

Bootstrapping Unsupervised Image Denoising with Parametric Noise Models (# 476)

Mangal Prakash, Manan Lalit, Pavel Tomancak, Alexander Krull, Florian Jug
MPI-CBG/CSBD,

17:45 18:00

Conference Closing: Announcement of Poster Awards

18:00 18:15 Room 1

Closing Reception

18:30 21:00 Reception Hall